The Buffalo Bills (0-0) face the Arizona Cardinals (0-0) on Sunday, September 8, 2024 at Highmark Stadium. The Bills are listed as favorites in this one, with the spread sitting at 6.5 points. The over/under is 47 in the contest.
Last year the Cardinals finished 4-13 and did not qualify for the postseason. On offense, they averaged 19.4 points per game (24th in league), and they allowed 26.8 per game (31st in NFL) on defense.
The Bills scored 26.5 points per game (sixth in NFL) and allowed 18.3 (fourth) last season, finishing 11-6 and getting knocked out of the playoffs in the Divisional round.
Cardinals vs Bills betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 5:00 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
- Spread Favorite: Buffalo (-6.5)
- Moneyline: Buffalo (-301), Arizona (+241)
- Total: 47 points
Cardinals betting insights
- In away games last season, Arizona was 3-5-1 against the spread, and 2-7 overall.
- The Cardinals posted a 8-8-1 record against the spread last year.
- Arizona had two wins ATS (2-4) on the road as 6.5-point underdogs or more.
- As 6.5-point underdogs or more, the Cardinals went 4-5 against the spread last year.
- Last season, in nine away games, Arizona hit the over three times.
- There were 10 Cardinals games (out of 17) that went over the total last year.
Cardinals leaders
- Kyler Murray: 1,799 PASS YDS / 224.9 YPG / 65.7% / 10 TD / 5 INT / 44 CAR / 244 RUSH YDS / 3 TD
- James Conner: 208 CAR / 1,040 YDS / 80.0 YPG / 7 TD / 27 REC / 165 YDS / 12.7 YPG / 2 TD
- Emari Demercado: 58 CAR / 284 YDS / 25.8 YPG / 2 TD / 21 REC / 119 YDS / 10.8 YPG / 0 TD
- Trey McBride: 81 REC / 825 YDS / 48.5 YPG / 3 TD
- Michael Wilson: 38 REC / 565 YDS / 43.5 YPG / 3 TD
- Chris Moore: 22 REC / 424 YDS / 28.3 YPG / 0 TD
Cardinals vs Bills game info
- Date: Sunday, September 8, 2024
- Time: 1:00 p.m. ET
- City: Orchard Park, New York
- Venue: Highmark Stadium
- TV Channel: CBS
- Live Stream: Fubo (Watch Bills vs Cardinals on Fubo)
- Live Stream: Watch on Paramount+
Watch the Arizona Cardinals all season on Fubo!