The Arizona Cardinals have one final game left this season, closing it out at home against the San Francisco 49ers.
Kickoff from State Farm Stadium is at 4:25 p.m. ET (2:25 p.m. Arizona time) and the game will air on FOX.
The Cardinals are 7-9 and have clinched third place in the NFC West. The Niners are 6-10 and finish in last place, no matter the outcome of this game.
Let’s have a look at the betting odds and lines for this Week 18 49ers vs. Cardinals matchup.
49ers at Cardinals Week 18 betting odds and lines
Odds come from BetMGM Sportsbook
Moneyline
- 49ers +165 (bet $100 to win $165)
- Cardinals -200 (bet $200 to win $100)
With these odds, the Cardinals are considered to be about 29% more likely to win the game than the 49ers.
The Cardinals are 5-3 at home and 2-3 against division opponents.
The 49ers are 2-5 on the road and 1-4 vs. the NFC West.
Spread
- 49ers +4 (-110)
- Cardinals -4 (-110)
A $110 ATS bet on the 49ers wins $100 if they win or tie the Cardinals, or if they lose by no more than three points.
A $110 ATS bet on the Cardinals wins $100 if they beat the Niners by five or more.
In the case of a four-point win by the Cardinals, it is a push and all bets are refunded.
The Cardinals are 10-6 ATS on the season while the Niners are 5-11 ATS.
Total
- Over 42.5 (-110)
- Under 42.5 (-110)
A $110 bet on the Over wins $100 if they combine for 43 or more points.
The same bet on the Under wins the same amount if they combine for 42 or fewer points.
The total was 49 in the Cardinals’ Week 5 win over the 49ers.
The 49ers are 9-6-1 O/U this season. The Cardinals are 7-8-1 O/U.
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